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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN5
All Species:
30.3
Human Site:
Y390
Identified Species:
60.61
UniProt:
O15484
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15484
NP_004046.2
640
73169
Y390
T
F
F
Q
N
P
Q
Y
I
F
E
V
K
K
P
Chimpanzee
Pan troglodytes
XP_001146965
641
74541
Y387
T
F
L
Q
N
P
Q
Y
I
F
T
V
P
E
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542293
640
73142
Y390
T
F
F
Q
N
P
Q
Y
I
F
D
V
K
K
P
Cat
Felis silvestris
Mouse
Mus musculus
O08688
640
72936
Y390
T
F
F
Q
N
P
Q
Y
V
F
E
V
K
K
P
Rat
Rattus norvegicus
Q8R4C0
640
73046
Y390
T
F
F
Q
N
P
Q
Y
I
F
E
V
K
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518356
408
46381
R182
Q
K
P
K
R
T
S
R
R
E
G
R
G
E
N
Chicken
Gallus gallus
Q92177
810
93542
Y453
T
F
W
T
N
P
Q
Y
R
L
K
L
L
E
E
Frog
Xenopus laevis
NP_001080808
642
73235
F390
T
Y
L
Q
N
P
Q
F
V
F
D
V
K
K
P
Zebra Danio
Brachydanio rerio
XP_001345114
642
73723
Y390
T
F
L
Q
N
P
Q
Y
V
F
D
V
R
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
Y434
T
F
W
H
N
P
Q
Y
I
I
T
L
V
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22036
648
73596
Y403
T
F
C
N
N
P
Q
Y
I
F
D
I
P
S
P
Sea Urchin
Strong. purpuratus
XP_792213
642
72430
F391
T
F
L
Q
N
P
Q
F
L
I
C
V
D
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
N.A.
92
N.A.
92.1
90.6
N.A.
51.4
30.8
73.9
71.6
N.A.
30.7
N.A.
40.1
47.6
Protein Similarity:
100
65.5
N.A.
95.6
N.A.
96
94.8
N.A.
57.3
46.9
86.2
83.8
N.A.
45.2
N.A.
57.2
64.9
P-Site Identity:
100
66.6
N.A.
93.3
N.A.
93.3
100
N.A.
0
40
66.6
66.6
N.A.
53.3
N.A.
60
46.6
P-Site Similarity:
100
73.3
N.A.
100
N.A.
100
100
N.A.
13.3
66.6
93.3
86.6
N.A.
66.6
N.A.
73.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
34
0
9
9
17
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
25
0
0
25
9
% E
% Phe:
0
84
34
0
0
0
0
17
0
67
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
50
17
0
9
0
0
0
% I
% Lys:
0
9
0
9
0
0
0
0
0
0
9
0
42
50
0
% K
% Leu:
0
0
34
0
0
0
0
0
9
9
0
17
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
92
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
9
0
0
92
0
0
0
0
0
0
17
0
59
% P
% Gln:
9
0
0
67
0
0
92
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
9
17
0
0
9
9
0
0
% R
% Ser:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% S
% Thr:
92
0
0
9
0
9
0
0
0
0
17
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
25
0
0
67
9
0
9
% V
% Trp:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _